He is on the books of Accra Hearts of Oak and wears shirt number 17. His main role on the pitch is Forward. His estimated market valuation currently stands at 125K €.

His latest transfer saw him join Accra Hearts of Oak from via on 2023-08-01.

During the Ghana Premier League 2025-2026 campaign, Hamza issah made 22 appearances, scoring 4 goals and adding 0 assists. He averaged 0.2 goals per match from 0 shots, with 0 on target.